Thyroid gland

• intra-thyroid thyroglossal duct cyst
  18 February 2017

  Open references
  Intra-thyroid thyroglossal duct cyst: a case report and review of literature.
  Huang LD, Gao SQ, Dai RJ, Chen DD, He B, Shi HQ, Yang K, Shan YF.
  Int J Clin Exp Pathol. 2015 Jun 1;8(6):7229-33. Review.
  PMID: #26261619# Free

• Warthin-like papillary thyroid carcinoma
  19 January 2017

  papillary thyroid carcinoma with Warthin tumor-like features; Warthin-like PTC; Warthin-like variant of papillary thyroid carcinoma; Warthin-like variant of PTC
  Images
  papillary thyroid carcinoma with Warthin tumor-like features
  https://twitter.com/chioseasi/status/820280183533998080
  https://twitter.com/aakasharmand/status/839855173325451264
  https://twitter.com/Kelly_MooneyMD/status/854683057575436288
  See also
  papillary thyroid carcinoma (PTC)
  Warthin tumor
  Open references (...)

• Turin criteria
  8 December 2016

  Turin proposal ; Turin classification
  The poorly differentiated thyroid carcinoma (PDTC) and anaplastic thyroid carcinoma (ATC) are aggressive thyroid tumors associated with a high mortality rate of 38-57 % and almost 100 % respectively.
  Paywall references
  Poorly differentiated thyroid carcinoma: 5 years after the 2004 WHO classification of endocrine tumours.
  Volante M, Papotti M.
  Endocr Pathol. 2010 Mar;21(1):1-6. doi: 10.1007/s12022-009-9100-4.
  PMID: #19960273#
  Poorly (...)

• atypical thyroid cytology
  28 November 2016

  atypical thyroid fine-needle aspiration
  Open references
  The atypical thyroid fine-needle aspiration: past, present, and future.
  Bongiovanni M, Krane JF, Cibas ES, Faquin WC.
  Cancer Cytopathol. 2012 Apr 25;120(2):73-86. doi: 10.1002/cncy.20178. Review.
  PMID: #21751429# Free
  Should "atypical follicular cells" in thyroid fine-needle aspirates be subclassified?
  Renshaw AA.
  Cancer Cytopathol. 2010 Aug 25;118(4):186-9. doi: 10.1002/cncy.20091. Erratum in: Cancer Cytopathol. 2010 Oct (...)

• thyroid follicular tumors
  28 November 2016

  folicular tumors of the thyroid gland
  Types
  thyroid follicular adenoma
  atypical thyroid follicular adenoma
  follicular thyroid carcinoma (FTC) MI-FTC minimally invasive-follicular thyroid carcinoma (FTC) WI-FTC widely invasive-follicular thyroid carcinoma (FTC)
  thyroid oncocytic tumors (Hurthle cell tumors )
  Open References
  A PCR-based expression signature of malignancy in follicular thyroid tumors.
  Foukakis T, Gusnanto A, Au AY, Höög A, Lui WO, Larsson C, Wallin G, (...)

• ThyraMIR
  14 November 2016

  Links
  ThyGenX and ThyraMIR at Interpace Diagnostics http://www.interpacediagnostics.com/

• GEC in thyroid FNA
  14 November 2016

  gene expression classifiers; GEC; Clinical diagnostic gene expression thyroid testing
  Examples
  Afirma GEC
  Paywall references
  Clinical diagnostic gene expression thyroid testing.
  Steward DL, Kloos RT.
  Otolaryngol Clin North Am. 2014 Aug;47(4):573-93. doi: 10.1016/j.otc.2014.04.009. Review.
  PMID: #25041959#

• Afirma
  14 November 2016

  Afirma GEC; Afirma gene expression classifier
  Afirma gene expression classifier / Afirma GEC
  See also
  molecular pathology of thyroid FNA
  Open references
  Afirma Benign Thyroid Nodules Show Similar Growth to Cytologically Benign Nodules During Follow-Up. Angell TE, Frates MC, Medici M, Liu X, Kwong N, Cibas ES, Kim MI, Marqusee E. J Clin Endocrinol Metab. 2015 Nov;100(11):E1477-83. doi:10.1210/jc.2015-2658. PMID: #26353010# Free
  Wide Inter-institutional Variation in Performance (...)

• ThyGenX
  14 November 2016

  ThyGenX
  Links
  ThyGenX and ThyraMIR at Interpace Diagnostics http://www.interpacediagnostics.com/
  Open references
  Molecular Testing of Thyroid Nodules: A Review of Current Available Tests for Fine-Needle Aspiration Specimens. Zhang M, Lin O. Arch Pathol Lab Med. 2016 Aug 24.
  PMID: #27557410# Free
  Paywall references
  Molecular cytopathology for thyroid nodules: A review of methodology and test performance. Nishino M. Cancer Cytopathol. 2016 Jan;124(1):14-27. (...)

• molecular pathology of thyroid cytology
  16 October 2016

  Thyroid FNA molecular studies
  Fine-needle aspiration (FNA) cytology is a common approach to evaluate thyroid nodules. It offers definitive diagnosis of a benign or malignant nodule in the majority of cases. However, 10-25% of nodules yield one of three indeterminate cytologic diagnoses, leading to suboptimal management of these patients.
  Atypia of undetermined significance/follicular lesion of undermined significance (AUS/FLUS) is a common indeterminate diagnosis, with the cancer risk (...)

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