Kidneys

• renal myoepithelial carcinoma
  3 November 2016

  renal MEC
  Molecular biology
  EWSR1-KLF15 fusion gene in renal myoepithelial carcinoma (#26523541#)
  Paywall references
  Expanding the Spectrum of Renal Tumors in Children: Primary Renal Myoepithelial Carcinomas With a Novel EWSR1-KLF15 Fusion. Cajaiba MM, Jennings LJ, Rohan SM, Leuer KM, Anagnost MR, Fahner JB, Fulton BK, Geller JI, Perlman EJ. Am J Surg Pathol. 2016 Mar;40(3):386-94. doi:10.1097/PAS.0000000000000545.
  PMID: (...)

• ALK-rearranged renal cell carcinoma
  1 November 2016

  ALK-rearranged RCC WKP
  Pathology
  ALK-STRN fusion gene in renal cell carcinoma (RCC) Anaplastic lymphoma kinase (ALK) translocation renal cell carcinomas (RCCs) have been reported: ALK-rearranged renal cell carcinoma (RCC) Striatin is a protein that in humans is encoded by the STRN gene.
  Paywall references
  Two Cases of Renal Cell Carcinoma Harboring a Novel STRN-ALK Fusion Gene. Kusano H, Togashi Y, Akiba J, Moriya F, Baba K, Matsuzaki N, Yuba Y, Shiraishi Y, Kanamaru H, Kuroda (...)

• renal undifferentiated sarcoma
  1 November 2016

  primary undifferentiated sarcoma of the kidney
  Molecular biology
  CIC-DUX4 gen fusion in primary undifferentiated sarcoma of the kidney (#27340751#)

• metanephric renal tumors
  19 October 2016

  Definition: The metanephric family of renal tumors encompasses metanephric adenofibroma , metanephric adenoma and metanephric stromal tumor ( in children).
  Examples
  metanephric adenoma
  https://twitter.com/sam_albadri/status/782604426598985729
  https://twitter.com/RyanneMDMBA/status/819746736537120768
  https://twitter.com/WebPathology/status/851903465806864385
  http://www.webpathology.com/case.asp?case=65
  Molecular pathology
  BRAF exon 15 mutations have been observed in 88% of (...)

• glomerular PEComa
  16 August 2016

  Examples
  14yoM.Tuberous Sclerosis.RBx (proteinuria) Glomerular "microPEComa"(Desmin+ HMB45+). No other MO lesions https://twitter.com/carles_saus/status/765531096360554496
  See also
  glomerular anomalies

• proximal convoluted tubule
  4 July 2016

  proximal convoluted tubule
  Images
  Transmission electron micrograph of the basal surface of the proximal convoluted tubule from a human. 20000x. https://twitter.com/Chapman_Histo/status/749840555035627520
  See also
  Kidney / Kidneys nephron

• renal apolipoprotein A4 amyloidosis.
  21 June 2016

  renal apolipoprotein A-IV amyloidosis
  Apolipoprotein A-IV associated amyloidosis (AApoAIV amyloidosis) is a rare cause of amyloidosis with only a single reported case.
  Renal AApoAIV amyloidosis typically presents with progressive chronic kidney disease and histologically exhibits extensive medullary involvement with sparing of the cortex.
  The diagnosis is best established by mass spectrometry. Hence, a high degree of suspicion and examination of the renal medulla is required to make the (...)

• diabetic nephropathy
  20 June 2016

  Images
  Diabetic nephropathy with prominent Kimmelstiel-Wilson nodules (PAS stain). https://twitter.com/BenMazer/status/860586085327482880
  Diabetic nephropathy https://twitter.com/dozing_dog/status/744723125393203201
  Extremely advanced diabetic nephropathy in a kidney : arterioles and nodular glomerulosclerosis / K-W nodules https://twitter.com/Gleason4plus5/status/750784164904001536
  See also
  diabetes
  renal diseases / (...)

• clear cell renal cell carcinoma
  20 June 2016

  ccRCC
  Images
  clear cell renal cell carcinoma https://twitter.com/pathobindotcom/status/510570786684301312
  See also
  renal cell carcinomas (RCCs)

• Sarcomatoid chromophobe RCC; scRCC
  16 June 2016

  Sarcomatoid chromophobe RCC; scRCC
  Images
  Sarcomatoid chromophobe RCC. CK7 is negative in the sarcomatoid component https://twitter.com/ESadimin/status/739898470283280385
  See also
  renal cell carcinomas chromophobe renal cell carcinoma

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