Skin

• diagnosis of adnexal tumors
  1 July 2004

  cutaneous appendage tumors; annexial tumors; cutaneous adnexal tumours
  See also : adnexal tumors
  Diagnosis by differentiation
  sweat gland derived
  eccrine gland derived : cutaneous eccrine tumors
  apocrine gland derived : cutaneous apocrine tumors
  hair follicles : hair follicle tumors > pilar tumors
  sebaceous glands : cutaneous sebaceous tumors
  Diagnosis by architectural pattern
  cystic adnexal tumors
  basaloid adnexal tumors
  squamoid adnexal tumors
  glandular adnexal tumors (...)

• combined nevus
  1 July 2004

  Histopathology:
  symmetric, well circumscribed
  2 or more of the following;
  — common nevus
  — blue nevus or other pigmented dendritic melanocytes
  — Spitz nevus (epithelioid and spindle cell nevus)
  — pigmented spindle and epithelioid cells
  — amelanotic spindle cells
  ordinary nevus component overlies/adjacent to other component
  deep involvement occurs
  plexiform configuration on occasion
  Differential:
  cellular blue nevus
  melanoma
  Return to: melanocytic (...)

• cutaneous melanocytic tumors
  1 July 2004

  Digital cases
  UI:1831 - dermal melanocytic nevus
  1. BASAL MELANOCYTE PROLIFERATION:
  lentigo simplex
  solar lentigo
  melanotic macule (labial and genital)
  PUVA lentigo
  lentiginous nevus
  2. MELANOCYTIC NEVI:
  common nevus (junctional, compound, intradermal)
  Meyerson nevus
  congenital nevus
  combined nevus
  inverted nevus
  recurrent nevus
  Halo nevus
  Spitz nevus (spindle and epithelioid cell nevus)
  pigmented spindle cell nevus (Reed nevus)
  deep-penetrating nevus (...)

• deep-penetrating nevus
  1 July 2004

  plexiform spindle cell nevus

• subepidermal blistering diseases
  30 June 2004

  subepidermal blistering, subepidermal bullous skin diseases

• linear IgA bullous dermatosis
  29 June 2004

  CLINICAL FEATURES:
  childhood onset within 5-6 years of birth (chronic bullous disease of childhood)
  adult onset in 6-8th decades
  often antecedent infection
  annular erythemaous patches with tense blisters at edges
  trunk and extremities most often affected
  HISTOPATHOLOGICAL FEATURES:
  subepidermal blister
  neutrophils linearly aligned along dermal-epidermal junction
  papillary dermal edema
  occasional eosinophils
  IMMUNOFLUORESCENCE:
  linear IgA and C3 (...)

• dermatitis herpetiformis
  29 June 2004

  herpetiform dermatitis PO
  Definition: Dermatitis herpetiformis is characterized by papules, vesicles, and occasional bullae on an erythematous, often urticarial base.
  Dermatitis herpetiformis is associated with gluten-sensitive enteropathy. It causes small pruritic vesicles.
  Histologically it shows papillary neutrophilic microabscesses and a mixed dermal inflammatory infiltrate. DIF shows a granular pattern of IgA in the dermal papillae.
  Digital cases
  UI:924 - Dermatitis (...)

• cutaneous squamous lesions
  28 June 2004
• cutaneous angiofibroma
  17 June 2004

  fibrous papule, adenoma sebaceum, pearly penile papules

• cutaneous lupus erythematosus
  17 June 2004

  Digital case
  JRC:10585 : Cutaneous lupus erythematosus.
  Images
  40F Asia x 10yrs, plenty of sun exposure. https://twitter.com/globaldermie/status/734923070532681732
  SUBTYPES
  systemic lupus erythematosus
  subacute cutaneous lupus erythematosus
  discoid lupus erythematosus
  neonatal lupus erythematosus
  DIFFERENTIAL
  dermatomyositis
  Sjogren syndrome
  lupus-like drug reactions
  polymorphous light eruptions
  Jessner’s lymphocytic infiltrate
  lichenoid actinic (...)

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