Anus

• anal squamous cell carcinoma
  1 May 2013

  anal epidermoid carcinoma
  80% of anal malignant tumors are squamous cell carcinomas (SCCs).
  Epidemiology
  Anal cancer is an uncommon malignancy, accounting for only about 4% of all cancers of the lower alimentary tract.
  The annual incidence is about 1 in 100,000. The incidence is higher in women and is increasing.
  Anal canal tumours are usually poorly differentiated. They are more common in women and have a worse prognosis.
  Systemic spread of anal cancer occurs in fewer than 10% of (...)

• anal tumors
  1 May 2013

  anal canal tumors
  Definition: 80% of anal cancers are squamous cell carcinomas (SCCs). Other tumour types include melanoma, lymphoma and adenocarcinoma. Tumour behaviour depends on its anatomical site of the primary cancer.
  Examples
  anal carcinomas
  anal melanoma

• anorectal lymphomas
  28 November 2012

  primary anorectal lymphomas
  Primary anorectal lymphoma is very rare with a higher incidence in human immunodeficiency virus positive (HIV+) patients. Most of these are high-grade B-cell non-Hodgkin lymphoma (NHL) associated with Epstein-Barr virus (EBV).
  Hodgkin lymphoma (HL) is also observed with a higher incidence in HIV+ patients and 100% are EBV+.
  Involvement of the colon and rectum accounts for approximately 20% of gastrointestinal HL in immunocompromised individuals.
  In HIV− (...)

• anal fistula
  30 March 2012

  Anal fistulae, anal fistule
  Definition: Anal fistula, or fistula-in-ano, is an abnormal connection between the epithelialised surface of the anal canal and (usually) the perianal skin.
  Anal fistulae are common and usually develop secondary to chronic infection of the anal glands or ducts. Many are idiopathic but they are also frequent in patients with Crohn disease and in occasional patients with ulcerative colitis.
  Anal fistulae originate from the anal glands, which are located between (...)

• anal fissure
  30 March 2012

  Anal fissures are common post-traumatic lesions, typically located posteriorly in the midline.
  An anal fissure is a break or tear in the skin of the anal canal.
  Anal fissures usually extend from the anal opening and are usually located posteriorly in the midline, probably because of the relatively unsupported nature and poor perfusion of the anal wall in that location.
  Fissure depth may be superficial or sometimes down to the underlying sphincter muscle.
  Epidemiology
  The incidence of (...)

• anorectal EBV-associated atypical lymphoproliferative disease
  23 December 2010

  Anorectal Epstein-Barr virus infection

• anal intraepithelial neoplasia
  30 November 2010

  AIN ; dysplasia of the squamous epithelium of the anus / perianal area; anal intra-epithelial neoplasia PO
  Images
  squamous epithelium in hemorrhoid sample : high grade anal intra-epithelial neoplasia. https://twitter.com/ARP_Press/status/877584719843532800
  The classification of anal intraepithelial neoplasia (AIN ) in mucosal biopsies is subject to considerable interobserver variability.
  Ki-67 labeling detects anal HPV-related changes with a high degree of sensitivity and (...)

• HPV-associated anal lesions
  30 November 2010

  The classification of anal intraepithelial neoplasia (AIN) in mucosal biopsies is subject to considerable interobserver variability. Ki-67 and p16/CDKN2A immunostains aid detection of dysplasia in biopsy samples from the uterine cervix.
  Ki-67 labeling detects anal HPV-related changes with a high degree of sensitivity and specificity, whereas increased p16/CDKN2A staining is strongly associated with high-grade squamous neoplasia. A combination of these markers may aid interpretation of anal (...)

• Morgagni crypt
  29 March 2009

  crypts of Morgagni

• recto-anal junction
  10 September 2007

  Videos
  Histology of the recto-anal junction (by Washington Deceit)
  See also
  digestive system

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