Cellular processes

Articles

• caspase-dependent cellular death
  20 April 2004

  References
  Abraham MC, Shaham S. Death without caspases, caspases without death. Trends Cell Biol. 2004 Apr;14(4):184-93. PMID: #15066636#

• neuronal growth
  24 August 2004

  Pathogenesis
  Once neurons have reached their correct destination, they need to extend axons and dendrites. Evidence is emerging that highlights the importance of the centrosome during axonal elongation and targeting.
  Once neuronal cell bodies have reached their final position, the centrosome seems to be crucial for organizing the cytoskeleton for axonal elongation and particle transport. For example, axonal growth depends on microtubule nucleation at the centrosome and the translocation (...)

• chromosomal segregation
  2 July 2004

  Proper chromosome segregation is required to maintain the appropriate number of chromosomes from one cell generation to the next and to prevent aneuploidy, the condition in which a cell has gained or lost one or several chromosomes during cell division.
  Aneuploidy is a hallmark associated with birth defects and cancer, and is observed at relatively high frequencies in human somatic cells.
  Recent studies in mammalian tissue culture cells suggest that the persistence of (...)

• cellular plasticity
  29 June 2004

  cell plasticity

• ciliogenesis
  20 March 2005

  References
  Bossinger O, Bachmann A. Ciliogenesis: polarity proteins on the move. Curr Biol. 2004 Oct 5;14(19):R844-6. PMID: #15458664#

• mRNA trafficking
  20 March 2005

  mRNA export

• chromosomal stability
  20 March 2005

  References
  Kapoor TM. Chromosome segregation: correcting improper attachment. Curr Biol. 2004 Dec 14;14(23):R1011-3. PMID: #15589138#
  Draviam VM, Xie S, Sorger PK. Chromosome segregation and genomic stability. Curr Opin Genet Dev. 2004 Apr;14(2):120-5. PMID: #15196457#
  Rajagopalan H, Nowak MA, Vogelstein B, Lengauer C. The significance of unstable chromosomes in colorectal cancer. Nat Rev Cancer. 2003 Sep;3(9):695-701. PMID: #12951588#
  Sieber OM, Heinimann K, Tomlinson IP. Genomic (...)

• cellular necrosis
  4 February 2006

  Necrosis refers to a spectrum of morphologic changes that follow cell death in living tissue, largely resulting from the progressive degradative action of enzymes on the lethally injured cell (cells placed immediately in fixative are dead but not necrotic).
  As commonly used, necrosis is the gross and histologic correlate of cell death occurring in the setting of irreversible exogenous injury. Necrotic cells are unable to maintain membrane integrity and their contents often leak out. This (...)

• mitoses
  13 July 2003

  mitosis
  Images
  in a glandular epithelium
  https://twitter.com/BeynonMD/status/740787261046919169
  in epidermis
  https://twitter.com/doctormisti/status/
  numerous atypical mitoses
  https://twitter.com/smlungpathguy/status/743442537763971073
  Pathology
  abnormal mitosis / abnormal mitoses
  quantitative variations
  no mitosis
  low mitotic activity
  moderate mitotic activity
  high mitotic activity
  See also
  mitotic spindle
  centrosomes
  cell cycle
  mitosis anomalies
  Videos (...)

• meiosis
  24 August 2004

  WP
  Definition: Meiosis is a specialized type of cell division leading to the production of gametes.
  During meiotic prophase I, homologous chromosomes interact with each other and form bivalents (pairs of homologous chromosomes).
  Three major meiotic processes — chromosome pairing, synapsis and recombination — are involved in the formation of bivalents.
  Chromosome pairing is largely dependent on the initiation and progression of recombination in fungi, mammals and plants, but not in (...)

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