Home > D. General pathology > Therapy, Toxics and drugs > etoposide
etoposide
Sunday 12 March 2006
Etoposide is a semisynthetic derivative of the podophyllotoxins, an epipodophyllotoxin. It inhibits DNA topoisomerase II, thereby inhibiting DNA synthesis.
Etoposide is cell cycle dependent and phase specific, affecting mainly the S and G2 phases.