Home > D. General pathology > Blood and immunity > Dysimmune diseases > sarcoidosis
sarcoidosis
Monday 22 September 2003
Sarcoidosis is a granulomatous disorder of unknown etiology, associated with an accumulation of CD4+ T cells and a TH1 immune response.
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Images
hepatic sarcoidosis
cutaneous sarcoidosis
Sarcoidosis: all types of giant cells and endogenous inclusions occur, none are specific
Links
Sarcoidosis in The Yale Rosen Collection of Pulmonary Pathology on Flickr
Localization
pulmonary sarcoidosis
nodal sarcoidosis
hepatic sarcoidosis
salivary sarcoidosis
Types
early-onset sarcoidosis
induced by recombinant interferon-alpha (IFN-alpha) (IFN-associated sarcoidosis) (15958865)
Susceptibility loci
truncating splice site mutation in BTNL2 gene (15735647)
CARD15 mutations in early-onset sarcoidosis
HLA-DRB1 locus (12934202)
References
Iannuzzi MC, Rybicki BA, Teirstein AS. Sarcoidosis. N Engl J Med. 2007 Nov 22;357(21):2153-65. PMID: 18032765