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nevus lipomatosus superficialis

Thursday 12 January 2006

naevus lipomatosus superficialis ; nevus lipomatosus cutaneous superficialis, Hoffmann-Zurhelle

WKP PO

Definition: Nevus lipomatosus superficialis (NLS) is a rare benign cutaneous hamartoma characterized by papules and nodules usually in the pelvic and sacral areas, with ectopic mature adipose tissue reaching the superficial dermis.

Images

 nevus lipomatosus superficialis

Synopsis

 Rare, benign cutaneous hamartoma
 @<@ 2y
 Multiple soft, papules, nodules, plaques
 Buttocks, upper thigh, lower back
 Normal epidermis
 Superficial dermis with lobules of adipocytes

Associations

 multiple folliculosebaceous cystic hamartomas (FCH) (15649197)
 dermoid cysts (15649197)
 perifollicular fibrosis (14721781)
 basal cell carcinoma (12786865)
 cavernous hemangioma (3074101)

Cytogenetics

 2p24 deletion (17223884)

See also

 Skin

References

 Cardot-Leccia N, Italiano A, Monteil MC, Basc E, Perrin C, Pedeutour F. Naevus lipomatosus superficialis: a case report with a 2p24 deletion. Br J Dermatol. 2007 Feb;156(2):380-1. PMID: 17223884

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