aplastic anemia

Etiology

 hereditary aplastic anemia

• Fanconi anemia
• dyskeratosis congenita
• Schwachman syndrome

 acquired aplastic anemia

• idiopathic (65%)
• chemicals (benzene, insecticides, solvents)
• drugs: chloramphenicol, phenylbutazone, anticonvulsants, gold
• radiation exposure
• immune-mediated hepatitis-associated aplastic anemia (HAAA)
• viruses
  • non-A non-B hepatitis
  • Epstein-Barr virus

• autoimmune disorders
  • rheumatoid arthritis
  • systemic lupus erythematosus

• pregnancy