eosinophilic esophagitis

Images

 Eosinophilic esophagitis

• https://twitter.com/Konzult_/status/733480083944574976
• https://twitter.com/amy_treece13/status/871513422499790848
• https://twitter.com/Konzult_/status/879515727685922817
• https://twitter.com/smallbluecells/status/879818589636833282

Synopsis

 eosoniphils in surface epithelium

• High number of eosinophils (>20/hpf)
• Eosinophil number highest proximally
• Predominance of eosinophils toward luminal surface
• eosinophilic microabscesses
• surface eosinophilic slough

 eosinophilic microabscess formation
 eosinophilic superficial concentration
 high intraepithelial eosinophil counts
 intraepithelial mast cells (17204948)
 IgE-bearing cells (17204948)

Differential diagnosis

 gastroesophageal reflux disease (GERD)

• peptic esophagitis

See also

 eosinophilic infiltrations
 eosinophilic digestive diseases
 eosinophilic gastroenteropathies
 esophagitis
 eosinophilic enteropathies

• eosinophilic enteritis
• eosinophilic gastritis

References

 Furuta GT, Liacouras CA, Collins MH, Gupta SK, Justinich C, Putnam PE, Bonis P, Hassall E, Straumann A, Rothenberg ME; First International Gastrointestinal Eosinophil Research Symposium (FIGERS) Subcommittees. Eosinophilic esophagitis in children and adults: a systematic review and consensus recommendations for diagnosis and treatment. Gastroenterology. 2007 Oct;133(4):1342-63. Epub 2007 Aug 8. PMID: 17919504

 Antonioli DA, Furuta GT. Allergic eosinophilic esophagitis: a primer for pathologists. Semin Diagn Pathol. 2005 Nov;22(4):266-72. PMID: 16939054

 Kirsch R, Bokhary R, Marcon MA, Cutz E. Activated mucosal mast cells differentiate eosinophilic (allergic) esophagitis from gastroesophageal reflux disease. J Pediatr Gastroenterol Nutr. 2007 Jan;44(1):20-6. PMID: 17204948