Home > G. Tumoral pathology > myofibroblastic tumors
myofibroblastic tumors
Monday 28 June 2004
myofibroblastic lesions, myofibroblastic tumor
Definition: subtype of fusiform cell tumors expressing a myofibroblastic differentiation and SMA smooth muscle actin.
Types
benign myofibroblastic tumors
- infantile myofibromatosis
- nodular fasciitis
- desmoid fibromatosis
- myofibroblastoma
intermeditae myofibroblastic tumors
malignant myofibroblastic tumors
- low-grade myofibroblastic sarcoma
- myofibrosarcoma
- plexiform fibrohistiocytic tumor
Examples
Inflammatory myofibroblastic tumor (IMT). IHC: ALK1. NB: spindle cell fascicles; prominent nucleoli; lymphoplasmacytosis.
See also
tumors
Paywall References
ALK expression in pseudosarcomatous myofibroblastic proliferations of the genitourinary tract. Hirsch MS, Dal Cin P, Fletcher CD. Histopathology. 2006 Apr;48(5):569-78. PMID: 16623783
Differential expression of smooth muscle myosin, smooth muscle actin, h-caldesmon, and calponin in the diagnosis of myofibroblastic and smooth muscle lesions of skin and soft tissue. Perez-Montiel MD, Plaza JA, Dominguez-Malagon H, Suster S. Am J Dermatopathol. 2006 Apr;28(2):105-11. PMID: 16625070
Fisher C. Myofibroblastic malignancies. Adv Anat Pathol. 2004 Jul;11(4):190-201. PMID: 15220822
