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meningioma

Wednesday 28 April 2004

meningiomas

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 meningioma

 lipomatous meningioma

Subtypes

 angiomatous meningioma (meningiomas whose vascular component exceeded 50% of the total tumor) (15104303)
 aggressive meningioma
 undifferentiated meningeal sarcoma
 clear cell meningioma
 lipomatous meningioma

LOH

 1p LOH
 9q LOH
 10q LOH
 14q LOH
 22q LOH

Gene mutations

 somatic mutations or deletions of NF2

References

 Perry A, Gutmann DH, Reifenberger G. Molecular pathogenesis of meningiomas. J Neurooncol. 2004 Nov;70(2):183-202. PMID: 15674477

 Lamszus K, Kluwe L, Matschke J, Meissner H, Laas R, Westphal M. Allelic losses at 1p, 9q, 10q, 14q, and 22q in the progression of aggressive meningiomas and undifferentiated meningeal sarcomas. Cancer Genet Cytogenet. 1999 Apr 15;110(2):103-10. PMID: 10214357