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airway-centered interstitial fibrosis

Monday 1 March 2004

Definition: Form of interstitial lung disease characterized pathologically by small airway-centered interstitial fibrosis and metaplastic bronchiolar epithelium extending around and often linking fibrotic and sometimes heavily muscularized bronchioles.

References

 Churg A, Myers J, Suarez T, Gaxiola M, Estrada A, Mejia M, Selman M. Airway-centered interstitial fibrosis: a distinct form of aggressive diffuse lung disease. Am J Surg Pathol. 2004 Jan;28(1):62-8. PMID: 14707865