apocrine tubular adenoma

Definition : Benign dermal adnexal neoplasm of apocrine derivation.

Differential diagnosis

 apocrine tumors

• apocrine cystadenoma : more dilated, cystic spaces rather than tubules
• papillary apocrine carcinoma : more cytologic atypia, irregular nuclear contours and a higher mitotic rate

 hidradenoma papilliferum

• often has complex arborizing papillae
• more closely arranged tumor cells and glands
• Limited to female genital region

 papillary eccrine adenoma: classically has features of eccrine rather than apocrine derivation; lacks decapitation secretion; different clinical presentation and distribution

 syringocystadenoma papilliferum:

• Usually connects to epidermis
• Fibrovascular cores within papillary structures
• Plasma cells within stroma

See also

 apocrine tumors