Myocarditis Associated With Immune Checkpoint Inhibitor Therapy

Synopsis

 significant and prominent interstitial inflammatory infiltrate composed of numerous histiocytes with interspersed lymphocytes.
 This lymphohistiocytic infiltrate was associated with evidence of myocardial injury.

• This included loss of myocyte nuclei, myocytes with irregular cell membranes with moth-eaten appearance, hypereosinophilia, and shrunken and irregular cardiac myocytes, but not associated with fibrosis .

Open references

 https://meridian.allenpress.com/aplm/article/144/11/1392/442293/Histopathologic-Characterization-of-Myocarditis