multiple trichoepitheliomas

See also : trichoepithelioma

Synopsis

 nests of basaloid cells

• Cells are often in fronds, may have 2 or more layers of basaloid cells.
• Cells may have papillary mesenchymal bodies.
• Basaloid cells form primitive hair follicle-germ structures (like cylindroma).

 They lack the myxoid stroma and artefactual clefting seen in basal cell carcinoma.
 Mitoses are uncommon when compared to basal cell carcinoma.

 fibromyxoid stroma

Variants

 desmoplastic trichoepithelioma

Predisposition - Association

 Rasmussen syndrome
 Brooke-spiegler syndrome
 Cowden syndrome

Differential diagnosis

 basaloid cell tumors

• basal cell carcinoma / BCC

For desmoplastic trichoepithelioma
 basal cell carcinoma, morphea type
 syringoma

See also

 cutaneous adnexal tumors

• pilar tumors