follicular thyroid tumors

Definition: Thyroid tumors with follicular architecture encompass a considerable array of distinct entities. These lesions share significant morphologic overlap, but portend different prognostic and therapeutic implications.

Due to their similar growth patterns, distinction between these tumors can be difficult; remarkable interobserver variability exists, even between expert endocrine pathologists.

Given the diagnostic challenges associated with these lesions, establishment of the correct diagnosis requires adequate gross examination protocol, careful attention to morphologic features and pathologic context, as well as—increasingly—adjunct molecular findings.

Open references

 Thyroid tumors with follicular architecture. doi : 10.1016/j.anndiagpath.2018.10.007
https://www.sciencedirect.com/science/article/pii/S1092913418303277