Home > A. Molecular pathology > immunoglobulin light chains
immunoglobulin light chains
Friday 12 December 2003
Pathology
light-chain-deposition disease
Pathogeny
Local microenvironmental conditions affect the ultrastructural organization of protein deposits. For example, pH influences the processing of immunoglobulin light chains, causing them to form either fibrillar amyloid aggregates or amorphous aggregates characteristic of light-chain-deposition disease.