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acute generalized exanthematous pustulosis

Tuesday 9 August 2016

AGEP

PO

Definition : AGEP is a pustular drug eruption.

Images

 Acute generalized exanthematous pustulosis (AGEP)

Synopsis

 subcorneal pustules
 spongiosis
 similar to pustular psoriasis but may have rare dermal eosinophils
 scattered epidermal neutrophils
 papillary dermal edema
 mixed dermal perivascular infiltrate, often associating eosinophils and neutrophils
 +/- necrotic keratinocytes

Etiology

 mifepristone-associated acute generalized exanthematous pustulosis

See also

 pustule
 pustulosis / pustuloses