cardiovascular Behçet disease

Behçet disease is an inflammatory disorder of unknown etiology showing diverse clinical presentations. Cardiac involvement is a critical problem that requires a timely diagnosis and management. Cardiac Behçet disease is presented as aortic valvulitis/aortitis or inflammatory mass lesion.

Synopsis

 severe aortic regurgitation with redundant prolapsing aortic cusps
 irregular mass lesions in the right ventricular cavity
 The aortic root is also involved with aortic valvulitis, showing severe mixed acute and chronic inflammation of various stages.
 There are frequent microabscess and extensive endothelial loss with fibrinous deposit.
 The right heart lesions shows similar histopathologic features

References

 Cardiac Behçet disease presenting as aortic valvulitis/aortitis or right heart inflammatory mass: a clinicopathologic study of 12 cases. Lee I, Park S, Hwang I, Kim MJ, Nah SS, Yoo B, Song JK. Am J Surg Pathol. 2008 Mar;32(3):390-8. doi : 10.1097/PAS.0b013e31814b23da PMID: 18300812