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eccrine syringofibroadenomae

Sunday 8 November 2020

eccrine syringofibroadenoma (of Mascaro), acrosyringeal adenomatosis
Eccrine poromatosis
Linear eccrine poroma
Acrosyringeal nevus of Weedon and Lewis
Nevus syringoadenomatosus papilliferum

PO

Definition : A rare benign eccrine proliferation with anastomosing cords in a fibrovascular stroma.

Synopsis

 anastomoting strands of epithelial cells
 anastomosing reticulated cords and strands of basaloid monomorphous cuboidal cells extending from the basal layer of epidermis into dermis
 cells are slightly smaller than neighboring keratinocytes
 loose fibrovascular stroma
 cords have scattered ductal structures resembling eccrine ducts lined by CEA+ cells
 +/- nests of clear cells

Differential diagnosis

 acrosyringeal nevus
 clear cell acanthoma
 CBC : fibroepithelioma of Pinkus
 poroma
 porocarcinoma