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lymphocytic hypophysitis

Friday 5 March 2010

Lymphocytic hypophysitis (LYH) is a rare autoimmune inflammatory disorder of the pituitary gland usually affecting young women, often in pregnancy or post partum period. It is rare in non-pregnant females and in men.

Synopsis

 expanding pituitary mass
 pituitary dysfunction

Associations

 bilateral dacryoadenitis (19726944)

Differential diagnosis

 Langerhans cell histiocytosis

References

 Lymphocytic hypophysitis with normal pituitary function mimicking a pituitary adenoma: a case report and review of literature. Rumana M, Kirmani A, Khursheed N, Besina S, Khalil M. Clin Neuropathol. 2010 Jan-Feb;29(1):26-31. PMID: 20040330