voltage-gated sodium channels

Voltage-gated sodium channels are essential for the generation and propagation of action potentials in striated muscle and neuronal tissues.

Biochemically, they consist of a large alpha subunit and 1 or 2 smaller beta subunits, such as SCN1B. The alpha subunit alone can exhibit all the functional attributes of a voltage-gated Na+ channel, but requires a beta-1 subunit for normal inactivation kinetics.

See also

 voltage-gated ion channels