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pleomorphic fibroma
Tuesday 14 October 2003
Pleomorphic fibroma is a benign fibroblastic tumor characterized by pleomorphic, hyperchromatic cells or giant multinucleated cells embedded in a collagenous stroma.
Localization
trunk extremities subungual (rare) (14507406)
Microscopical synopsis
paucicellular tumor hyperchromatic spindled, pleomorphic, floret-like giant cells embedded in haphazardly arranged collagen bundles in the dermis no mitotic figures
Immunochemistry
vimentin + S-100 - cytokeratin - smooth muscle actin - factor XIIIa - CD34 -