lithium-associated parathyroid tumors

See also

 parathyroid tumors
 lithium-associated hyperparathyroidism (HPT)
 comparative genomic hybridization (CGH)
 loss of heterozygosity (LOH)
 multiple endocrine neoplasia type 1 (MEN1)

CGH

 losses

• 1p
• 11
• 15q
• 22q

 gains

• X chromosome

LOH

 11q13 LOH

Somatic gene mutations

 somatic MEN1 mutation

Cancer loci

 MEN1 loci
 1p34.3-pter
 1q21-q32

References

 Dwight T, Kytola S, Teh BT, Theodosopoulos G, Richardson AL, Philips J, Twigg S, Delbridge L, Marsh DJ, Nelson AE, Larsson C, Robinson BG. Genetic analysis of lithium-associated parathyroid tumors. Eur J Endocrinol. 2002 May;146(5):619-27. PMID: #11980616#