Home > A. Molecular pathology > glutathione S-transferase

glutathione S-transferase

Wednesday 15 November 2006

Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione.

Based on their biochemical, immunologic, and structural properties, the soluble human GSTs are categorized into 4 main classes: alpha (GSTAs), mu (GSTMs), pi (GSTPs), theta (GSTTs) and zeta (GSTZs).