B. Cellular pathology

• lipoblast-like cells
  13 June 2017

  lipoblast-like appearance; lipoblast-like change
  Examples
  lipoblasts

• clear cell changes
  13 June 2017

  Synopsis
  voluminous clear cytoplasm glycogen-rich cytoplasm lipid-rich cytoplasm
  Examples
  clear cell tumors

• bizarre nuclei
  13 June 2017

  See also
  pleomorphic nuclei
  nuclear anomalies

• pyknosis
  13 June 2017

  See also
  nuclear anomalies

• cytoplasmic anomalies
  13 June 2017

  Examples
  cross striations
  cytoplasmic eosinophilia
  cytoplasmic basophilia
  cytoplasmic vacuolation
  clear cytoplasm / clear cell change
  cytoplasmic eosinophilia
  cytoplasmic inclusions
  See also
  morphological anomalies microscopical anomalies nuclear anomalies
  See also
  cellular anomalies nuclear anomalies

• microvilli
  4 May 2017

  (singular: microvillus) WKP
  Definition: Microvilli are microscopic cellular membrane protrusions that increase the surface area for diffusion and minimize any increase in volume, and are involved in a wide variety of functions , including absorption , secretion , cellular adhesion , and mechanotransduction.
  Examples
  enterocytic microvilli

• oncocytic cells
  3 May 2017

  oncocytic cell: Hürthle cell
  See also : oncocytic metaplasia
  In some circumstances, oncocytic change is a feature of tumours that have a benign behaviour, such as oncocytic renal cell tumors.
  Parathyroid gland
  Parathyroid tumours with oncocytic change were thought to have reduced functional capacity for hormone production. This has not been substantiated because there are cases of hormone hypersecretion in patients with these lesions, and immunohistochemical studies show that these (...)

• cellular differentiation
  3 May 2017

  Transcriptional programs control cellular lineage commitment and differentiation during development.
  RNA-seq
  Understanding of cell fate has been advanced by studying single-cell RNA-sequencing (RNA-seq) but is limited by the assumptions of current analytic methods regarding the structure of data.
  The single-cell topological data analysis (scTDA) is an algorithm for topology-based computational analyses to study temporal, unbiased transcriptional regulation.
  Unlike other methods, scTDA (...)

• nuclear bubbles
  2 May 2017

  nuclear pseudopseudoinclusions
  See also
  nuclear inclusions nuclear pseudoinclusions

• abnormal cells
  6 April 2017

  abnormal cell
  Examples
  morphologically abnormal cells tumoral cells
  functionnaly abnormal cells
  See also
  cells
  anomalies

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