Genital system

• granulosa-theca cell tumor
  13 February 2006

  granulosa-stromal cell tumors
  Digital case
  JRC:18776 : Adrenal gland granulosa, theca tumor (F, 52 y/o)
  Granulosa cell tumors (GCTs) are composed of granulosa cells, theca cells, and fibroblasts in varying amounts and combinations. The term "granulosa-theca cell tumor" had been applied to all tumors in which both cell types were identified, regardless of the amounts present.
  Young and Scully proposed a system that required a tumor to be composed of at least 25% of the second cell type (...)

• Leydig cell tumor
  13 February 2006

  Leydig cell adenoma
  Digital cases
  HPC:119 : Leydig cell tumor.
  JRC:18782 : Testis intestitial cell tumor
  Images
  Leydig cell tumor
  https://twitter.com/MayoClinicPath/status/743120235230699520
  https://twitter.com/seattlequinns/status/857024877034848256
  Synopsis
  Leydig cell proliferation
  round cell proliferation
  fusiform cell proliferation
  Leydig cells
  abundant eosinophilic cytoplasm
  characteristic nuclear-rich zones separated by nuclear-free zones
  crystals of Reinke (...)

• Sertoli-Leydig cell tumor
  13 February 2006

  Sertoli-Leydig cell tumours of the ovary and testis; Sertoli-leydig tumor
  Images
  Sertoli-leydig cell tumor
  https://twitter.com/StanfordPath/status/748343921856520192
  https://twitter.com/jachavez23/status/832429855371296768
  https://twitter.com/seattlequinns/status/857027916185587713
  https://twitter.com/amy_treece13/status/875448332599967745
  Digital cases
  JRC:1455 : Ovary Sertoli-Leydig cell tumor (poorly differentiated, with heterologous mucinous component).
  JRC:9205 : Ovary (...)

• XX-agonadism
  9 February 2006

  XX-gonadal agenesis

• sexual precocity
  31 January 2006

  References
  Root AW. Sexual precocity: a historical perspective and update. Fetal Pediatr Pathol. 2005 Jan-Feb;24(1):39-62. PMID: #16175751#

• gametogenesis
  31 January 2006

  Definition: Gametogenesis is the development of diploid germ cells into either haploid eggs or sperm, (respectively oogenesis and spermatogenesis). It is different for each species but the general stages are similar.
  The oogenesis and the spermatogenesis have many features in common, they both involve:
  meiosis
  extensive morphological differentiation
  incapacity of surviving for very long if fertilization does not occur.
  Despite their homologies they also have major differences: (...)

• ambiguous genitalia
  21 January 2006

  Disorders of sex development (DSDs) are congenital conditions in which the development of chromosomal, gonadal, or anatomic sex is atypical.
  DSDs with ambiguous genitalia are typically diagnosed at clinical examination in infancy, whereas those associated with male and female phenotypes may be diagnosed much later.
  DSDs can be classified broadly into four categories on the basis of gonadal histologic features:
  female pseudohermaphroditism (46,XX with two ovaries);
  male (...)

• gonadal ridge
  20 January 2006

  genital ridge

• genital development
  20 January 2006

  genital duct development

• genital ducts
  20 January 2006

  See also
  genital duct development

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