Digital Pathology Cases

Articles

• pleuropulmonary blastoma
  13 November 2003

  pediatric pneumoblastoma, pulmonary blastoma of childhhod, PPB
  Definition: Pleuropulmonary blastoma (PPB) is a rare malignant mesenchymal tumor of lung parenchyma and/or pleura in young children.
  Pleuropulmonary blastoma is an aggressive tumor characterized by mesenchymal elements (including undifferentiated blastema and often cartilaginous, rhabdomyoblastic, or fibroblastic differentiation) and epithelium-lined spaces.
  Images
  Pleuropulmonary blastoma (PPB) (...)

• focal myositis
  5 May 2009

  Digital cases
  UI:638 - Myositis ossificans
  Definition: Focal myositis is an uncommon inflammatory pseudotumor of skeletal muscle that can be confused with a variety of neoplastic and inflammatory diseases.
  It is often misunderstood because it presents as a tumor-like mass, but histologically resembles a skeletal muscle myopathy or dystrophy.
  Focal myositis occurs in specific muscle groups of young adults of both sexes without significant trauma.
  It is a largely unrecognized entity (...)

• gonadoblastoma
  11 March 2004

  Scully RE, 1953.

• testicular germ cell tumors
  13 June 2006

  testicular germ cell cancer.

• Ewing sarcoma
  21 May 2004

  Ewing tumor, Ewing tumour
  Images
  Ewing’s sarcoma https://twitter.com/MArnold_PedPath/status/740720267647942656 https://twitter.com/histiocytosisX/status/779419664120152064 https://twitter.com/histiocytosisX/status/880130635909799936
  Digital cases (Digital slides)
  HPC:31 : Ewing sarcoma
  HPC:132 : Ewing sarcoma
  HPC:182 : Ewing sarcoma
  HPC:376 : EWSR1-FLI1+ bone-forming Ewing sarcoma (EWSR1-FLI1+ small cell osteosarcoma)
  Variants
  epithelioid Ewing sarcoma
  spindle cell Ewing (...)

• thymoma
  15 September 2004

  thymomas WP WebPathology PO
  Definition: Thymoma is the most frequent tumor arising in human thymus (thymic tumors). Thymoma is a tumor originating from the epithelial cells of the thymus.
  Images
  Thymoma / Notes https://twitter.com/GeronimoJrLapac/status/812328746967568384
  Digital cases
  JRC:477 : Thymoma with micronodular features
  JRC:1607 : Thymoma (differential diagnosis. lymphohistiocytoid mesothelioma).
  JRC:3189 : Thymic carcinoma. Thymoma, type C.
  JRC:3190 : Mixed (...)

• epithelioid hemangioma of the bone
  31 January 2011

  epithelioid hemangioma of bones

• alveolar architecture
  7 December 2012

  tumoral alveolar architectural pattern; pseudoalveolar pattern ; alveolar pattern
  Digital cases
  JRC:3169 : Alveolar soft-part sarcoma.
  JRC:11247 : Alveolar soft-part sarcoma.
  Images
  alveolar soft part sarcoma (ASPS). IHC: +TFE3. NB: pseudoalveolar pattern w/ central discoherence; vascular invasion a common finding https://twitter.com/histiocytosisX/status/797916878018482177 https://twitter.com/DCSkipperDO/status/694718706715377664
  alveolar soft part sarcoma (...)

• Niemann-Pick disease type B
  15 August 2012

  NPDB; acid sphingomyelinase deficiency
  Definition: NPD type B is a rare inborn error of metabolism of autosomal recessive inheritance. Patients with Niemann-Pick disease type B (NPDB) have a benign course and prognosis. It is mainly a visceral form without neurologic manifestations despite the massive visceral involvement. NPDB is caused by mutations in the acid lysosomal sphingomyelin phosphodiesterase-1 gene (SMPD1) (MIM.607608)
  Digital slides
  Case 52 (HPC:52) : Liver in (...)

• neurocristic hamartoma
  30 April 2010

  neurocristic cutaneous hamartoma, cutaneous neurocristic hamartoma

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