tumoral architecture

See also : tumoral patterns

Examples

 micronodular pattern in Kaposi sarcoma

• https://twitter.com/bunn_belinda/status/742098640089546752

 indian file pattern

• https://twitter.com/solcosao/status/709243596134744065

Types

 single cells

 compact pattern / solid pattern

• clusters
• anastomosing beads

 trabecular pattern (trabecular tumors )

• cords / corded pattern
• indian file pattern

 tufted pattern
  papillary pattern (papillary tumors )
 tubular pattern (tubular tumors )
 tubulopapillary pattern (tubulopapillary tumors )
 leaf-like pattern / leaf-like architecture /
 diffuse pattern (compact pattern or solid pattern )
 scleronodular pattern (scleronodular tumors )
 herringbone pattern
 staghorn pattern
 plexiform pattern (plexiform tumors )
 hemangiopericytic pattern
 angular pattern
 lobular pattern (lobular tumors )

• myxoid and lobular tumors

 alveolar pattern (alveolar tumors )
 glandular pattern (glandular tumors )

• acinar pattern (acinar tumors )
• adenomatous pattern (adenomatous tumors )

 microcystic pattern
 micronodular pattern
 dual composition (biphasic tumors)
 circular or oval formations
 microacini
 cribriform pattern / microcribriform pattern
 glomerular pattern
 targetoid whirls
 rosettes
 cylindromatous differentiation
 insular architecture / insular pattern
 palisaded architecture / palisaded pattern
 sheet-like architecture

 intercellular background

• myxoid tumors
  • myxoid and lobular tumors

Tumoral formations

 whorl formations
 circular formations
 oval formations
 tumoral clefts
 tumoral laceworks
 tumoral bone formation
 tumoral calcifications

Areas

 spindle cell areas (spindle cell tumors)
 myxoid areas (myxoid tumors)

• myxoid and lobular tumors

Appearance of cellular sheets

 sheets of small round cells
 sheets of small cells with eccentric nuclei
 sheets of large round cells
 sheets of large cells with eccentric nuclei and abundant eosinophilic cytoplasm (myoid cells)
 sheets of spindle cells
 sheets of strap cells
 sheets of stellate cells

Tumoral architectural patterns (examples)

 papillary pattern

• papillary thyroid carcinoma (PTC )
• papillary renal cell carcinoma (PRCC )

 tubular pattern

• tubulous adenoma
• adenocarcinomas

 trabecular pattern

• endocrine carcinomas
  • carcinoid tumors
  • paragangliomas (pheochromocytoma )

 solid pattern or compact pattern

 scleronodular pattern

• scleronodular Hodgkin lymphoma

 herringbone pattern

• fibrosarcomas
• synovialosarcoma

 hemangiopericytomatous pattern

• infantile myofibromatosis
• solitary fibrous tumor (SFT )

See also

 tumoral patterns
 growth patterns
 microarchitecture
 tissular architecture

References

 Potter JD. Morphogens, morphostats, microarchitecture and malignancy. Nat Rev Cancer. 2007 Jun;7(6):464-74. PMID: 17522715

Books

 Tumors: An atlas of differential diagnosis, by Cyril Toker. University Park Press, Baltimore, 1983. ISBN: 0839118120