Home > E. Pathology by systems > Skin > congenital nevus
congenital nevus
Friday 2 December 2022
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Synopsis
Tends to involve reticular dermis, subcutis, skin adnexa, arrector pili muscles and nerves with single cell permeation of collagen
Also neural differentiation with Wagner-Meissner-like corpuscles
Frequent proliferative nodules
Lesions of infants may have pagetoid melanocytic proliferation
Proliferative nodules:
- Dermal nodules of large epithelioid or spindled melanocytes that merge with surrounding nevus cells
- Often prominent nucleoli, cellular areas, focal hemorrhage and ulceration but no necrosis, no destructive growth, minimal inflammation and 0 - 4 mitotic figures/10 HPF
- Lesions mature and regress over time
Differential diagnosis
glomus tumor
malignant melanoma