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nodular hidradenoma

Friday 28 August 2020

hidradenoma, eccrine acrospiroma

PO

Synopsis

 nests / lobules of cells resembling eccrine poroma with either clear cytoplasm or prominent squamous metaplasia
 possible marked vascularity
 small and large lumina are lined by cuboidal ductal cells or columnar secretory cells
 cystic spaces may be due to degeneration of tumor cells

Images

 https://twitter.com/SkinPathology/status/638584069907857409
 https://twitter.com/TexPathol/status/1038034487647633408

Differential diagnosis

 apocrine mixed tumor
 glomus tumor (different staining pattern)
 cutaneous metastasis / metastatic disease ( clear cell renal cell carcinoma )
 primary skin tumors with follicular differentiation
 tumors with sebaceous differentiation
 tumors with sweat gland differentiation