Home > E. Pathology by systems > Skin > Clark level
Clark level
Wednesday 9 October 2019
Clark’s level
WKP |
Definition : Clark’s level is a staging system, used in conjunction with Breslow depth , which describes the level of anatomical invasion of the melanoma in the skin.
Five anatomical levels are recognized, and higher levels have worsening prognostic implications. These levels are:
Level 1: Melanoma confined to the epidermis ( melanoma in situ )
Level 2: Invasion into the papillary dermis
Level 3: Invasion to the junction of the papillary and reticular dermis
Level 4: Invasion into the reticular dermis
Level 5: Invasion into the subcutaneous fat / hypodermis
Images