ovarian serous borderline tumor

Images

 http://www.webpathology.com/image.asp?n=24&Case;=525
 Wikimedia: serous borderline tumor with micropapillary pattern

 Ovarian serous borderline tumor with focal microinvasion

• https://twitter.com/JustineVarinot/status/815848948103598080

Differential diagnosis

 benign serous papillary cystadenoma

• may have focal areas of atypia suggestive, but not diagnostic of borderline tumor

 serous carcinoma

• low grade tumors may have similar appearance, but have destructive stromal invasion

 mucinous borderline tumors

• epithelium is mucinous;
• mixed tumors have mucinous, squamous or endometrioid differentiation, often associated with endometriosis

 ovarian clear cell carcinoma

• may have papillary features, but are unilateral, associated with endometriosis;
• have nonhierarchical branching, monomorphic cells with classic features elsewhere, focal cytologic atypia (Am J Surg Pathol 2008;32:269)

See also

 ovarian tumors

• ovarian serous tumors

Reference

 Molecular subtypes of serous borderline ovarian tumor show distinct expression patterns of benign tumor and malignant tumor-associated signatures. Curry EW, Stronach EA, Rama NR, Wang YY, Gabra H, El-Bahrawy MA. Mod Pathol. 2013 Aug 16. doi : 10.1038/modpathol.2013.130 PMID: 23948749