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ASC-US

Monday 8 April 2013

ASCUS : Atypical squamous cells of undetermined significance

WHO : https://screening.iarc.fr/atlasglossdef.php?key=ASC-US&img;

Types

 intermediate cell with an enlarged nucleus and a homogenous chromatin
 eosinophilic squamous cell with enlarged and hyperchromatic nucleus
 eosinophilic squamous cell with an enlarged nucleus but with pale chromatin
 intermediate cells with an enlarged nucleus and a chromatin slightly denser
 squamous cell with eosinophilic cytoplasm and an enlarged nucleus and a non densified chromatin
 intermediate squamous cell with an enlarged nucleus and a cytoplasmic clearing
 basophilic squamous cells with enlarged and slightly hyperchromatic nuclei
 eosinophilic squamous cells with enlarged nuclei and cytoplasmic clearing
 intermediate cell with an enlarged, regular nucleus and a homogenous chromatin, surrounded by an ill-defined clear halo
 binucleated eosinophilic cell with a dense, homogenous chromatin
 squamous metaplastic cells from the deep intermediate layers with nuclear enlargement
 superficial eosinophilic cell with enlarged and irregular nucleus
 intermediate cell with a mildly densifiied and an enlarged nucleus with a small perinuclear halo

Images

 https://screening.iarc.fr/atlascyto_detail.php?flag=0⟨=1&Id;=cyt14536&cat;=F1a1a

Differential diagnosis

 CIN 3 Pap/Biopsy Correlation Case by Ed Euthman

See also

 ASC : atypical squamous cells

  • ASC-H : atypical squamous cells cannot exclude HSIL