signet ring cells

Etiology

 signet ring cell change

• digestive mucosal injury

 signet ring cell tumors

• signet ring cell carcinomas

Images

 digestive mucosal injury leads to slough of benign mucinous cells. Beware of signet ring cell change in benign polyps, stomach, and pseudomembranous colitis

• https://twitter.com/RhondaYantiss/status/876834829794455552

See also

 signet ring-like cell / signet ring-like cells

References

 Sung CO, Seo JW, Kim KM, Do IG, Kim SW, Park CK. Clinical significance of signet-ring cells in colorectal mucinous adenocarcinoma. Mod Pathol. 2008 Oct 10. PMID: 18849918

 Wang K, Weinrach D, Lal A, Musunuri S, Ramirez J, Ozer O, Keh P, Rao MS. Signet-ring cell change versus signet-ring cell carcinoma: a comparative analysis. Am J Surg Pathol. 2003 Nov;27(11):1429-33.
PMID: 14576475